Concepedia

Neutrophil-like pH-responsive pro-efferocytic nanoparticles improve neurological recovery by promoting erythrophagocytosis after intracerebral hemorrhage

Linfeng Fan, Lulu Jin, Tianchi Tang, Yonghe Zheng, Zihang Chen, Haopu Lin, Chao Ding, Tingting Wang, Huaijun Chen, Yinghan Guo,

Theranostics · 2023 · 46 citations · 54 references

DOIFull text

Open access

Concepts

Abstract

This biomimetic nanomedicine is envisaged to offer an encouraging strategy to effectively promote hematoma and inflammation resolution, consequently alleviate ICH progression.

References

54

Phagocytosis and clearance of apoptotic cells is mediated by MER

Rona S. Scott, Eileen McMahon, Shannon M. Pop et al. · Nature · 2001 · 1.2K citations

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Neutrophil membrane-coated nanoparticles inhibit synovial inflammation and alleviate joint damage in inflammatory arthritis

Qiangzhe Zhang, Diana Dehaini, Yue Zhang et al. · Nature Nanotechnology · 2018 · 947 citations

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Apoptotic Cells Promote Their Own Clearance and Immune Tolerance through Activation of the Nuclear Receptor LXR

Noelia A-González, Steven J. Bensinger, Cynthia Hong et al. · Immunity · 2009 · 668 citations · Full text

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Loss of Phospholipid Asymmetry and Surface Exposure of Phosphatidylserine Is Required for Phagocytosis of Apoptotic Cells by Macrophages and Fibroblasts

Valerie A. Fadok, Aimee de Cathelineau, David L. Daleke et al. · Journal of Biological Chemistry · 2001 · 637 citations · Full text

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Phosphatidylserine exposure and red cell viability in red cell aging and in hemolytic anemia

F. Edward Boas, Linda Forman, Ernest Beutler · Proceedings of the National Academy of Sciences · 1998 · 402 citations

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