Concepedia

TRAF4 regulates ubiquitination-modulated survivin turnover and confers radioresistance

Jinzhuang Liao, Qing Xiang, Gan Yu, Ruirui Wang, Shuangze Han, Wěi Li, Wei Song

International Journal of Biological Sciences · 2023 · 17 citations · 49 references

DOIFull text

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Concepts

Abstract

and the xenograft mouse model. Altogether, our study highlights the TRAF4-survivin axis as a potential therapeutic target for radiosensitization in NPC.

References

49

Long non-coding RNA PVT1 predicts poor prognosis and induces radioresistance by regulating DNA repair and cell apoptosis in nasopharyngeal carcinoma

Yi He, Yizhou Jing, Fang Wei et al. · Cell Death and Disease · 2018 · 192 citations · Full text

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A phase I/II study of sepantronium bromide (YM155, survivin suppressor) with paclitaxel and carboplatin in patients with advanced non-small-cell lung cancer

Ronan J. Kelly, Anish Thomas, Arun Rajan et al. · Annals of Oncology · 2013 · 172 citations · Full text

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Degradation of Survivin by the X-linked Inhibitor of Apoptosis (XIAP)-XAF1 Complex

Vinay A. Arora, Herman H. Cheung, Stéphanie Plenchette et al. · Journal of Biological Chemistry · 2007 · 164 citations · Full text

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TRAF4 Is a Critical Molecule for Akt Activation in Lung Cancer

Wei Li, Cong Peng, Mee‐Hyun Lee et al. · Cancer Research · 2013 · 118 citations · Full text

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LncRNA linc00312 suppresses radiotherapy resistance by targeting DNA-PKcs and impairing DNA damage repair in nasopharyngeal carcinoma

Zhen Guo, Youhong Wang, Heng Xu et al. · Cell Death and Disease · 2021 · 117 citations · Full text

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