Exploring the potential therapeutic value of Solanum lycopersicum L. phytoconstituents for Parkinson's disease through molecular docking analysis

Abstract

Parkinson's disease is a neurodegenerative disorder characterized by the loss of dopaminergic neurons in the brain, leading to motor and non-motor symptoms. The search for novel therapeutic agents to mitigate the progression of the disease and alleviate its symptoms has led to the exploration of natural compounds. Solanum lycopersicum L., commonly known as tomato, contains various phytoconstituents that have shown promise in neuroprotection and anti-inflammatory properties. This study aims to investigate the potential therapeutic value of Solanum lycopersicum L. phytoconstituents for Parkinson's disease through a comprehensive molecular docking analysis. Using state-of-the-art computational techniques, we will evaluate the binding interactions between these phytoconstituents and key protein targets associated with Parkinson's disease. The findings from this research may contribute to the development of new therapeutic strategies and drug candidates for the management of Parkinson's disease.