HMGB1 induces hepcidin upregulation in astrocytes and causes an acute iron surge and subsequent ferroptosis in the postischemic brain

Hepcidin Regulates Cellular Iron Efflux by Binding to Ferroportin and Inducing Its Internalization

Elizabeta Nemeth, Marie S. Tuttle, Julie Powelson et al. · Science · 2004 · 4.7K citations

Iron Metabolism, Immunology, Molecular Biology +20

Dysmetabolic Hyperferritinemia: All Iron Overload Is Not Hemochromatosis

Jasbir Makker, Ahmad Hanif, Bharat Bajantri et al. · Case Reports in Gastroenterology · 2015 · 1.4K citations · Full text

Ferrostatins Inhibit Oxidative Lipid Damage and Cell Death in Diverse Disease Models

Rachid Skouta, Scott J. Dixon, Jianlin Wang et al. · Journal of the American Chemical Society · 2014 · 1.1K citations · Full text

Oxysterol, Biochemistry, Medicine +14

Tau-mediated iron export prevents ferroptotic damage after ischemic stroke

Qing‐zhang Tuo, Peng Lei, K A Jackman et al. · Molecular Psychiatry · 2017 · 703 citations · Full text

Ischemic Stroke, Biochemistry, Medicine +11

Mutually exclusive redox forms of HMGB1 promote cell recruitment or proinflammatory cytokine release

Emilie Vénéreau, Maura Casalgrandi, Milena Schiraldi et al. · The Journal of Experimental Medicine · 2012 · 691 citations · Full text

Inflammation, Cytokine, Redox Signaling +15