Concepedia

Initiation and Up-Titration of Guideline-Based Medications in Hospitalized Acute Heart Failure Patients　― A Report From the West Tokyo Heart Failure Registry ―

Takanori Ohata, Nozomi Niimi, Yasuyuki Shiraishi, Ichiro Umemura, Takashi Kohno, Yuji Nagatomo, Makoto Takei, Tomohiko Ono, Munehisa Sakamoto, Shintaro Nakano,

Circulation Journal · 2023 · 14 citations · 35 references

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Abstract

Significant evidence-practice gaps in the use and dose of GDMT remain. Considering the associated favorable outcomes, further efforts to improve its implementation seem crucial.

References

35

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The Effect of Spironolactone on Morbidity and Mortality in Patients with Severe Heart Failure

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Angiotensin–Neprilysin Inhibition versus Enalapril in Heart Failure

John J.V. McMurray, Milton Packer, Akshay S. Desai et al. · New England Journal of Medicine · 2014 · 6.6K citations · Full text

Effects of Enalapril on Mortality in Severe Congestive Heart Failure

New England Journal of Medicine · 1987 · 5.1K citations

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Cardiovascular and Renal Outcomes with Empagliflozin in Heart Failure

Milton Packer, Stefan D. Anker, Javed Butler et al. · New England Journal of Medicine · 2020 · 4.7K citations · Full text