Concepedia

The efficacy and safety of cannabidiol as adjunct treatment for drug-resistant idiopathic epilepsy in 51 dogs: A double-blinded crossover study

Aaron J. Rozental, Brooke G. Weisbeck, Isabella Corsato Alvarenga, Daniel L. Gustafson, Breonna Kusick, Sangeeta Rao, Lisa R. Bartner, Stephanie McGrath

Journal of Veterinary Internal Medicine · 2023 · 23 citations · 45 references

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Abstract

Cannabidiol decreased total seizures and seizure days compared to placebo when administered to dogs PO at 9 mg/kg/day. Liver enzymes should be monitored with administration of CBD in dogs.

References

45

Trial of Cannabidiol for Drug-Resistant Seizures in the Dravet Syndrome

Orrin Devinsky, J. Helen Cross, Linda Laux et al. · New England Journal of Medicine · 2017 · 1.6K citations · Full text

Treatment Outcomes in Patients With Newly Diagnosed Epilepsy Treated With Established and New Antiepileptic Drugs

Zhibin Chen, Martin J. Brodie, Danny Liew et al. · JAMA Neurology · 2017 · 1.4K citations

Effect of Cannabidiol on Drop Seizures in the Lennox–Gastaut Syndrome

Orrin Devinsky, Anup D. Patel, J. Helen Cross et al. · New England Journal of Medicine · 2018 · 948 citations · Full text

Cannabidiol in patients with seizures associated with Lennox-Gastaut syndrome (GWPCARE4): a randomised, double-blind, placebo-controlled phase 3 trial

Elizabeth A. Thiele, Eric D. Marsh, Jacqueline A. French et al. · The Lancet · 2018 · 868 citations

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Development and validation of a questionnaire for measuring behavior and temperament traits in pet dogs

Yuying Hsu, James A. Serpell · Journal of the American Veterinary Medical Association · 2003 · 676 citations