Concepedia

Halogen-bonding-mediated synthesis of amides and peptides

Mingqin Huang, Junjie Li, Chi Zhang

Green Chemistry · 2023 · 10 citations · 50 references

DOI

Concepts

Abstract

We report the first methods for halogen-bonding-mediated formation of amide and peptide bonds. The methods can be used to synthesize not only amides but also dipeptides, tripeptides and pentapeptides in good to excellent yields without racemization.

References

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