Concepedia

Publication | Open Access

<i>HLA-DPA1*02:01~B1*01:01</i> is a risk haplotype for primary sclerosing cholangitis mediating activation of NKp44+ NK cells

DOIFull Paper Access

14

Citations

50

References

2023

Year

Britta Franziska Zecher, David Ellinghaus, Sebastian Schloer, Annika Niehrs, Benedetta Padoan, Martin E. Baumdick, Yuko Yuki, Maureen P. Martin, Jennifer Schröder‐Schwarz, Jennifer Niersch,
Gut

Abstract

Our studies identify a novel PSC risk haplotype <i>HLA-DP A1*02:01~DPB1*01:01</i> and provide clinical and functional data implicating NKp44+NK cells that recognise HLA-DPA1*02:01-DPB1*01:01 expressed on cholangiocytes in PSC pathogenesis.

References

YearCitations

Page 1