Asian Journal of Organic Chemistry · 2023 · 22 citations · 103 references
Natural SciencesChemistryMedicinal ChemistryDrug DiscoveryOrganic ChemistrySynthetic Medicinal ChemistryHeterocycle SynthesisHeterocyclic ChemistryOrganic SynthesisChemical Synthesis Of AnaloguesHeterocyclic Medicinal ChemistryMedicinal Chemistry ApplicationsMedicinal HeterocyclesOrganic Substrates
Abstract Phenanthridines are a privileged heterocyclic compound that exists in many natural products and has been known to exhibit a variety of pharmacological properties. In the last few decades, an incredible development has taken place to synthesise this scaffold. In this regard, 2‐isocyanobiphenyl has become one of the most exploited substrates that allow the direct formation of phenanthridine derivatives under various novel and conventional methods. The present review provides an overview of synthetic approaches for the preparation of phenanthridine, and their derivatives form 2‐isocyanobiphenyls′′.
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Total Synthesis of Ecteinascidin 743
Atsushi Endo, Arata Yanagisawa, Masanao Abe et al. · Journal of the American Chemical Society · 2002 · 288 citations