Antinociceptive effect of gelsenicine, principal toxic alkaloids of gelsemium, on prostaglandin E2-induced hyperalgesia in mice: Comparison with gelsemine and koumine

Interleukin-1β-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity

Tarek A. Samad, Kimberly A. Moore, Adam Sapirstein et al. · Nature · 2001 · 1.3K citations

Inflammation, Interleukin-1β-mediated Induction, Pain Syndrome +13

GlyR α3: An Essential Target for Spinal PGE ₂ -Mediated Inflammatory Pain Sensitization

Ulrike B. Depner, Heinz Wässle, Seifollah Ahmadi et al. · Science · 2004 · 601 citations

Pain Medicine, Spinal Pge2 Injection, Immunology +16

Up‐regulation of cyclooxygenase‐2 mRNA in the rat spinal cord following peripheral inflammation

Flora Beiche, Stefan Scheuerer, Kay Brune et al. · FEBS Letters · 1996 · 328 citations · Full text

PGE2 selectively blocks inhibitory glycinergic neurotransmission onto rat superficial dorsal horn neurons

Seifollah Ahmadi, Sebastian Lippross, Winfried Neuhuber et al. · Nature Neuroscience · 2001 · 304 citations

Medicine, Synaptic Transmission, Physiology +12

Allodynia evoked by intrathecal administration of prostaglandin E2 to conscious mice

Toshiaki Minami, Rumiko Uda, S Horiguchi et al. · Pain · 1994 · 128 citations

Anesthetic Mechanism, Pharmacotherapy, Glucocorticoid +17