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Publication | Open Access

PERK Inhibition by HC-5404 Sensitizes Renal Cell Carcinoma Tumor Models to Antiangiogenic Tyrosine Kinase Inhibitors

DOIFull Paper Access

22

Citations

36

References

2023

Year

Michael E. Stokes, Verónica Calvo, Sho Fujisawa, Crissy Dudgeon, Sharon Huang, Nupur Ballal, Leyi Shen, Jennifer Gasparek, Matthew J. Betzenhauser, S. Taylor,
Clinical Cancer Research

Abstract

By disrupting an adaptive stress response evoked by VEGFR-TKI, HC-5404 presents a clinical opportunity to improve the antitumor effects of well-established standard-of-care therapies in RCC.

References

YearCitations

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