Concepedia

Age-associated disparity in phagocytic clearance affects the efficacy of cancer nanotherapeutics

Yifan Wang, Weiye Deng, DaeYong Lee, Yan Long, Yifei Lü, Shiyan Dong, Kristin Huntoon, Abin Antony, Xuefeng Li, Rui Ye,

Nature Nanotechnology · 2023 · 43 citations · 30 references

Open access

Concepts

Life SciencesImmunologyOncologyAgingCancer ImmunologyInnate ImmunityCancer ImmunotherapyCancer NanomedicineCell-nanoparticle InteractionsNanomedicineTumor Immune MicroenvironmentTumor-associated MacrophagesAge-related Cancer BiologyCancer NanotherapyClearance In Cancer MicroenvironmentsImmune Evasion By NanoparticlesNanoparticle ClearanceNanoparticle-based ChemotherapyPhagocytic Activity

References

30

Tissue-based map of the human proteome

Mathias Uhlén, Linn Fagerberg, Björn M. Hallström et al. · Science · 2015 · 15.9K citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +17

Principles of nanoparticle design for overcoming biological barriers to drug delivery

Elvin Blanco, Haifa Shen, Mauro Ferrari · Nature Biotechnology · 2015 · 6.7K citations · Full text

Pharmacy, Biomedical Engineering, Pharmaceutics +16

Phase III Trial of Nanoparticle Albumin-Bound Paclitaxel Compared With Polyethylated Castor Oil–Based Paclitaxel in Women With Breast Cancer

William J. Gradishar, Sergei Tjulandin, Neville Davidson et al. · Journal of Clinical Oncology · 2005 · 2.1K citations · Full text

Pharmacy, Oncology, Pharmacology +15

Synthetic nanoparticles functionalized with biomimetic leukocyte membranes possess cell-like functions

Alessandro Parodi, Nicoletta Quattrocchi, Anne L. van de Ven et al. · Nature Nanotechnology · 2012 · 1.1K citations · Full text

Life Sciences, Biomedical Engineering, Immunology +16

The Tabula Sapiens: A multiple-organ, single-cell transcriptomic atlas of humans

Robert C. Jones, Jim Karkanias, Mark A. Krasnow et al. · Science · 2022 · 999 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17