Concepedia

KDM5A noncanonically binds antagonists MLL1/2 to mediate gene regulation and promotes epithelial to mesenchymal transition

R. Kirtana, Soumen K. Manna, Samir Kumar Patra

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · 2023 · 12 citations · 25 references

DOI

Concepts

References

25

Active genes are tri-methylated at K4 of histone H3

Helena Santos-Rosa, Robert Schneider, Andrew J. Bannister et al. · Nature · 2002 · 2.2K citations

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Genome-wide Mapping of HATs and HDACs Reveals Distinct Functions in Active and Inactive Genes

Zhibin Wang, Chongzhi Zang, Kairong Cui et al. · Cell · 2009 · 1.4K citations · Full text

, , +11

Mll2 is required for H3K4 trimethylation on bivalent promoters in embryonic stem cells, whereas Mll1 is redundant

Sergei Denissov, Helmut Hofemeister, Hendrik Marks et al. · Development · 2014 · 295 citations · Full text

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Interplay between HDAC3 and WDR5 Is Essential for Hypoxia-Induced Epithelial-Mesenchymal Transition

Min-Zu Wu, Ya-Ping Tsai, Muh‐Hwa Yang et al. · Molecular Cell · 2011 · 274 citations · Full text

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Histone Lysine Demethylase JARID1a Activates CLOCK-BMAL1 and Influences the Circadian Clock

Luciano DiTacchio, Hiep D. Le, Christopher Vollmers et al. · Science · 2011 · 242 citations

, , +17