Concepedia

Box–Behnken design of thermo-responsive nano-liposomes loaded with a platinum(<scp>iv</scp>) anticancer complex: evaluation of cytotoxicity and apoptotic pathways in triple negative breast cancer cells

Nada K. Sedky, Maria Braoudaki, Noha Khalil Mahdy, Kenzy Amin, Iten M. Fawzy, Eleni Κ. Efthimiadou, R.A. Youness, Sherif Ashraf Fahmy

Nanoscale Advances · 2023 · 40 citations · 48 references

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Concepts

Abstract

by 70% and 85%, respectively. As such, the optimal Asp TLs (40 °C) treatment displayed the most potent cytotoxic profile and induced both apoptosis and necrosis in MDA-MB-231.

References

48

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

Freddie Bray, Jacques Ferlay, Isabelle Soerjomataram et al. · CA A Cancer Journal for Clinicians · 2018 · 87.7K citations · Full text

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Analyzing real-time PCR data by the comparative CT method

Thomas D. Schmittgen, Kenneth J. Livak · Nature Protocols · 2008 · 26.7K citations

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Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death

Zoltán N. Oltval, Curt Milliman, Stanley J. Korsmeyer · Cell · 1993 · 6K citations

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Drug Delivery Systems: Entering the Mainstream

Theresa M. Allen, Pieter R. Cullis · Science · 2004 · 4.5K citations

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Structure of Bcl-x <sub>L</sub> -Bak Peptide Complex: Recognition Between Regulators of Apoptosis

Michael Sattler, Heng Liang, David G. Nettesheim et al. · Science · 1997 · 1.5K citations

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