World Journal of Clinical Cases · 2023 · 15 citations · 9 references
PharmacyClinical ToxicologyToxicologyHemodialysisPoisoning DiagnosisPoisoning ManagementDrug Overdose ManagementMultiorgan DysfunctionMultiorgan FailureOverdose ManagementContinuous HemodialysisMultiorgan Failure ManagementMultiorgan Failure SupportParaquat PoisoningSystematic Literature ReviewTreatment Strategies
BACKGROUND: With the withdrawal of paraquat from the market, diquat is widely used, so the treatment of diquat poisoning has become one of the focuses of emergency poisoning diagnosis and treatment. CASE SUMMARY: We studied the case of a 17-year-old male patient who drank 200 mL (20 g/100 mL) of diquat solution two hours before arriving at the hospital. Despite the use of treatments such as gastric lavage, hemoperfusion, continuous hemodialysis, glucocorticoids, and organ support, the patient's condition rapidly progressed to multiorgan failure, and he died 23.5 h after admission. CONCLUSION: We summarized the clinical characteristics and treatment strategies of diquat poisoning through this case and performed a literature review to provide a basis and direction for clinical treatment.
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Evidence for energy-dependent accumulation of paraquat into rat lung
Michael S. Rose, Lewis L. Smith, I. Wyatt · Nature · 1974 · 296 citations
Pharmacy, Pharmacology, Physiology +11
[Research advance in CD147 and acute lung injury].
Caiming Xu, Hailong Chen · PubMed · 2013 · 173 citations
Acute diquat poisoning resulting in toxic encephalopathy: a report of three cases
Guangcai Yu, Tianzi Jian, Siqi Cui et al. · Clinical Toxicology · 2022 · 50 citations · Full text
Pharmacy, Neurology, Toxicology +14