Elevated Expression of Two Pore Potassium Channel THIK-1 in Alzheimer’s Disease: An Inflammatory Mechanism

Abstract

The association between THIK-1 K+ channels expression and pathology changes indicates a THIK-1-induced activation of this glial subtype in AD and PD. Therefore, specific blocks of the microglial THIK-1 K+ channels at the early stage of AD and PD may be beneficial for the patients.