Gypenoside Pretreatment Alleviates the Cerebral Ischemia Injury via Inhibiting the Microglia-Mediated Neuroinflammation

Neurotoxic reactive astrocytes are induced by activated microglia

Shane A. Liddelow, Kevin A. Guttenplan, Laura Clarke et al. · Nature · 2017 · 8K citations · Full text

Medicine, Neurobiology, Neuroscience +14

Global, regional, and national burden of stroke and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

Valery L. Feigin, Benjamin Stark, Catherine O. Johnson et al. · The Lancet Neurology · 2021 · 7.6K citations · Full text

Public Health, Health Sciences, Epidemiologic Methods +16

HIF‐1 is expressed in normoxic tissue and displays an organ‐specific regulation under systemic hypoxia

Deborah Stroka, Tobias Burkhardt, Isabelle Desbaillets et al. · The FASEB Journal · 2001 · 720 citations · Full text

Medicine, Cell Biology, Molecular Biology +17

NFκB-Activated Astroglial Release of Complement C3 Compromises Neuronal Morphology and Function Associated with Alzheimer’s Disease

Hong Lian, Li Yang, Allysa Cole et al. · Neuron · 2014 · 702 citations · Full text

Life Sciences, Neurobiology, Neuroscience +16

Inhibition of Stat3‐mediated astrogliosis ameliorates pathology in an Alzheimer's disease model

Nicole Reichenbach, Andrea Delekate, Monika Plescher et al. · EMBO Molecular Medicine · 2019 · 366 citations · Full text

Medicine, Neurology, Neuroscience +17