Concepedia

Lignin/Puerarin Nanoparticle-Incorporated Hydrogel Improves Angiogenesis through Puerarin-Induced Autophagy Activation

Yingjing Pan, Longquan Shao, Yulin Zhang, Han Qiao, Liyuan Sheng, Rui Guo, Ting Sun, Yanli Zhang

International Journal of Nanomedicine · 2023 · 16 citations · 41 references

DOIFull text

Open access

Abstract

The puerarin-attached lignin nanoparticle-incorporated hydrogel effectively alleviated blood perfusion in mice with hind-limb ischemia. Puerarin has a prominent proangiogenic effect. The potential mechanisms might be that puerarin-mediated autophagy activation and increase in PPARβ/δ.

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