Macromolecular Chemistry and Physics · 2023 · 16 citations · 48 references
EngineeringBioengineeringBiomedical EngineeringBiomaterialsBiosensorsDrug DeliveryBiomedical SensorsBlood Glucose MonitoringContinuous Glucose MonitoringDiabetes ManagementGelsHydrogelsBiosensingBlood Glucose RegulationDesign PrinciplesGlucose BiosensingGlucose MonitoringGlucose SensorsHydrogel CharacterizationTherapeutic Efficacy Assessment
Abstract Diabetes mellitus is one of the key diseases of clinical concern that can lead to a variety of serious complications and it is characterized by increased blood glucose levels. Glucose‐sensitive hydrogel is gaining attention as a smart hydrogel capable of sensing glucose molecules for diabetes and related complications. In order to better understand this hydrogel, this paper reviews its basic design principles and focuses on the therapeutic efficacy of this hydrogel in delivering insulin, drugs, and bioactives for diabetes and diabetes‐related complications. Its use as a biosensing device for glucose measurement in body fluids and dynamic monitoring of wounds is also presented, and its potential application in the treatment of diabetes and related diseases is highly summarized.
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Core–Shell Microneedle Gel for Self-Regulated Insulin Delivery
Jinqiang Wang, Yanqi Ye, Jicheng Yu et al. · ACS Nano · 2018 · 287 citations · Full text