Reduced <scp>Cortico‐Cortical Resting‐State</scp> Connectivity in Sensory Systems Related to Bodily Pain in Juvenile Fibromyalgia

Abstract

Reduced cortico-cortical sensory integration involving PCL/S1 and spanning the sensory systems may underly critical pain sensory features in youth with JFM. Reduced sensory integration is paralleled by augmented cross-talk between sensory and affective/salience-processing regions, potentially indicating a shift toward more affectively colored sensory experiences to the detriment of specific sensory discrimination.