Concepedia

Publication | Open Access

CRISPR/dCAS9-mediated DNA demethylation screen identifies functional epigenetic determinants of colorectal cancer

DOIFull Paper Access

10

Citations

44

References

2023

Year

Juan Ramón Tejedor, Alfonso Peñarroya, Javier Gancedo-Verdejo, Pablo Santamarina‐Ojeda, Raúl F. Pérez, Sara López-Tamargo, Ana Díez-Borge, Juan José Alba‐Linares, Nerea González-del-Rey, Rocío G. Urdinguio,
Clinical Epigenetics

Abstract

These results highlight the potential role of DNA methylation as a driver mechanism of CRC and paves the way for the identification of novel therapeutic windows based on the epigenetic reactivation of certain tumour suppressor genes.

References

YearCitations

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