Concepedia

Microfluidic organotypic device to test intestinal mucosal barrier permeability <i>ex vivo</i>

Amanda E. Cherwin, Hayley Templeton, Alexis Ehrlich, Brielle H Patlin, Charles S. Henry, Stuart Tobet

Lab on a Chip · 2023 · 10 citations · 20 references

DOIFull text

Open access

Concepts

Abstract

model system offers promise for further studies exploring factors that affect gut barrier integrity and potential downstream consequences that cannot be studied in current models.

References

20

Microfluidic organs-on-chips

Sangeeta N. Bhatia, Donald E. Ingber · Nature Biotechnology · 2014 · 3.2K citations

Human gut-on-a-chip inhabited by microbial flora that experiences intestinal peristalsis-like motions and flow

Hyun Jung Kim, Dongeun Huh, Geraldine A. Hamilton et al. · Lab on a Chip · 2012 · 1.7K citations

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Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer

Thomas R. Cox, Janine T. Erler · Disease Models & Mechanisms · 2011 · 1.6K citations · Full text

, , +17

Claudin-based tight junctions are crucial for the mammalian epidermal barrier

Mikio Furuse, Masaki Hata, Kyoko Furuse et al. · The Journal of Cell Biology · 2002 · 1.5K citations · Full text

, , +13

Intestinal Barrier Dysfunction, LPS Translocation, and Disease Development

Siddhartha S. Ghosh, Jing Wang, Paul J. Yannie et al. · Journal of the Endocrine Society · 2020 · 697 citations · Full text

, , +17