Risks of Ventricular Arrhythmia and Heart Failure in Carriers of <i>RBM20</i> Variants

Abstract

<i>RBM20</i> variants are associated with a high risk of MVA and ESHF compared with idiopathic left ventricular systolic dysfunction. The risk of MVA in male and female <i>RBM20</i> variant carriers is similar, but male sex is strongly associated with ESHF.