Mechanism of anticancer effect of gambogic acid on gastric signet ring cell carcinoma

Gambogic Acid Induces Apoptosis and Regulates Expressions of Bax and Bcl-2 Protein in Human Gastric Carcinoma MGC-803 Cells

Li Zhao, Qing-Long Guo, Qi-Dong You et al. · Biological and Pharmaceutical Bulletin · 2004 · 184 citations · Full text

Life Sciences, Oncology, Pharmacology +17

Association between Oxidative DNA Damage and Risk of Colorectal Cancer: Sensitive Determination of Urinary 8-Hydroxy-2′-deoxyguanosine by UPLC-MS/MS Analysis

Cheng Guo, Xiaofen Li, Rong Wang et al. · Scientific Reports · 2016 · 146 citations · Full text

Pharmacy, Oncology, Toxicology +17

Anticancer effect and apoptosis induction of gambogic acid in human gastric cancer line BGC-823

Wei Liu · World Journal of Gastroenterology · 2005 · 117 citations · Full text

Medicine, Oncology, Pharmacology +17

General gambogic acids inhibited growth of human hepatoma SMMC-7721 cells in vitro and in nude mice.

Qing Guo, Qi You, Z. Wu et al. · PubMed · 2004 · 103 citations

Medicine, Cancer Biology, Pharmacology +9

Gambogic acid is an antagonist of antiapoptotic Bcl-2 family proteins

Dayong Zhai, Chaofang Jin, Chung-Wai Shiau et al. · Molecular Cancer Therapeutics · 2008 · 82 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +16