<scp>SETD1A</scp>‐mediated <scp>H3K4me3</scp> methylation upregulates <scp>lncRNA HOXC‐AS3</scp> and the binding of <scp>HOXC‐AS3</scp> to <scp>EP300</scp> and increases <scp>EP300</scp> stability to suppress the ferroptosis of <scp>NSCLC</scp> cells

Abstract

SETD1A-mediated H3K4me2 methylation promoted HOXC-AS3 expression, binding of HOXC-AS3 to EP300, and EP300 stability, thereby suppressing NSCLC cell ferroptosis.