Genetic and pharmacological inhibition of METTL3 alleviates renal fibrosis by reducing EVL m6A modification through an IGF2BP2‐dependent mechanism - Concepedia

Concepedia

Publication | Open Access

Genetic and pharmacological inhibition of METTL3 alleviates renal fibrosis by reducing EVL m6A modification through an IGF2BP2‐dependent mechanism

DOI Full Paper Access

44

Citations

30

References

2023

Year

Wei‐Jian Ni, Hong Zhou, Hao Lu, Nan‐Nan Ma, Bingbing Hou, Wei Li, Fan‐Xu Kong, Ju‐Tao Yu, Rui Hou, Juan Jin,

Clinical and Translational Medicine

Abstract

Collectively, the overactivated METTL3/EVL m6A axis is a potential target for renal fibrosis therapy, and the pharmacological inhibition of METTL3 activity by isoforsythiaside suggests that it is a promising anti-renal fibrosis agent.

References

	Year	Citations

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