Initial Panitumumab Plus Fluorouracil, Leucovorin, and Oxaliplatin or Plus Fluorouracil and Leucovorin in Elderly Patients With RAS and BRAF Wild-Type Metastatic Colorectal Cancer: The PANDA Trial by the GONO Foundation

Abstract

Both mFOLFOX and 5-FU + LV + PAN are reasonable options as initial therapy of elderly patients with <i>RAS</i>/<i>BRAF</i> wild-type mCRC. 5-FU + LV + PAN is associated with a better safety profile.