Journal of Huntington s Disease · 2023 · 37 citations · 12 references
Life SciencesNeurologyNeuroscienceNeurodegenerationNeurogeneticsClinical TrialsGenetic DisordersHuntington DiseaseNeurodegenerative Disease GeneticsNeurodegenerative DiseasesNeurodegenerative DisordersRandomized Clinical Trials
In this edition of the Huntington's Disease Clinical Trials Corner, we expand on the GENERATION HD2 (tominersen) and on the Asklepios Biopharmaceutical/BrainVectis trial with AB-1001. We also comment on the recent findings from the PROOF-HD trial, and list all currently registered and ongoing clinical trials in Huntington's disease.
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Justo García de Yébenes, G. Bernhard Landwehrmeyer, Ferdinando Squitieri et al. · The Lancet Neurology · 2011 · 172 citations
Medicine, Neurology, Pharmacology +13
Motor, cognitive, and functional declines contribute to a single progressive factor in early HD
Scott Schobel, Giuseppe Palermo, Peggy Auinger et al. · Neurology · 2017 · 155 citations · Full text
Medicine, Neurology, Neuroscience +17
CYP46A1 gene therapy deciphers the role of brain cholesterol metabolism in Huntington’s disease
Radhia Kacher, Antonin Lamazière, Nicolas Heck et al. · Brain · 2019 · 112 citations · Full text