MucoUp® as a spacer in brachytherapy for uterine cervical cancer: A first-in-human experience

Yoichi Muramoto, Naoya Murakami, Tatsuki Karino, Satoru Sugimoto, Jun Takatsu, Masaki Oshima, Yasuo Kosugi, Terufumi Kawamoto, Takashi Hirayama, Kazunari Fujino,

Clinical and Translational Radiation Oncology · 2023 · 10 citations · 24 references

DOIFull text

Open access

Concepts

Abstract

We first used MucoUp®, a hyaluronic acid used in endoscopic resection, as a spacer in brachytherapy. In five cervical cancer patients, MucoUp® insertion increased a 90% dose of the high-risk CTV to over 80 Gy while decreasing the dose of organs at risk. No related adverse events were observed.

References

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