Upregulation of A20 and TAX1BP1 contributes to the anti-neuroinflammatory and antidepressant effects of bavachalcone

Inhibition of NF-κB Signaling by A20 Through Disruption of Ubiquitin Enzyme Complexes

Noula Shembade, Averil Ma, Edward W. Harhaj · Science · 2010 · 665 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Lipopolysaccharide-induced blood-brain barrier disruption: roles of cyclooxygenase, oxidative stress, neuroinflammation, and elements of the neurovascular unit

William A. Banks, Alicia M. Gray, Michelle A. Erickson et al. · Journal of Neuroinflammation · 2015 · 625 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

The E3 ligase Itch negatively regulates inflammatory signaling pathways by controlling the function of the ubiquitin-editing enzyme A20

Noula Shembade, Nicole S. Harhaj, Neal G. Copeland et al. · Nature Immunology · 2008 · 270 citations

Life Sciences, Biochemistry, Molecular Biology +14

Ibrutinib alleviates LPS-induced neuroinflammation and synaptic defects in a mouse model of depression

Weifen Li, Tahir Ali, Kaiwu He et al. · Brain Behavior and Immunity · 2020 · 258 citations

Life Sciences, Neuroscience, Pharmacology +16

Direct, Noncatalytic Mechanism of IKK Inhibition by A20

Brian Skaug, Jueqi Chen, Fenghe Du et al. · Molecular Cell · 2011 · 249 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +10