Long-Term Weight Changes After Starting Anti–IL-5/5Ra Biologics in Severe Asthma: The Role of Oral Corticosteroids

Abstract

Anti-IL-5/5Ra therapy is associated with long-term weight reduction, especially in patients with higher OCS exposure before treatment and those able to reduce OCS use during treatment. However, the effect is small and does not apply to all patients, and so additional interventions seem necessary if weight change is desired.