Clinical Nuclear Medicine · 2023 · 16 citations · 9 references
MedicineOncologyPharmacologyMetastasisPain ManagementRadionuclide TherapyBone MetastasisBone Metastasis PainMetastatic Bone DiseaseMetastatic Cancer ManagementMetastatic Disease TreatmentProstate CancerBone Metastases ManagementBone Metastasis Pain ControlBone Metastasis Response AssessmentBone Metastasis TherapyBone Pain PalliationMetastatic Bone Disease ManagementRefractory Cancer PainRefractory Pain Syndromes
ABSTRACT: Bone is the most common metastatic site in patients with prostate cancer. 177Lu-DOTA-ibandronic acid (177Lu-DOTA-IBA) is a new therapeutic radiopharmaceutical targeting bone metastasis. We report a case of refractory bone pain due to bone metastasis, who demonstrated an excellent therapy response after 3 cycles of 177Lu-DOTA-IBA therapy. In addition, the patient did not have any observable adverse reactions. 177Lu-DOTA-IBA may be a promising radiopharmaceutical for the treatment of bone metastasis.
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Preparation, biological characterization and preliminary human imaging studies of 68Ga-DOTA-IBA
Yingwei Wang, Qixin Wang, Zan Chen et al. · Frontiers in Oncology · 2022 · 39 citations · Full text
Ambreen Khawar, Elisabeth Eppard, Frank Roesch et al. · Annals of Nuclear Medicine · 2019 · 38 citations