A High Performance Enzyme-Free Glucose Sensor Based on the Graphene-CuO Nanocomposites

Abstract

Graphene-CuO nanocomposites were synthesized on a template of graphene by a one-step chemical synthesis approach and used to fabricate an enzyme-free amperometric glucose sensor. The fabricated glucose sensor showed that the linear dependence was from 2.0 μM to 0.06 mM, with high sensitivity of 1480 μA mM-1 cm-2, fast response time of 3 s and low detection limit of 0.29 μM (S/N=3). Furthermore, the sensor is highly resistant against poisoning by chloride ion; the interference from the common interfering species such as ascorbic acid (AA), dopamine (DA), uric acid (UA) can be effectively avoided; the sensor also displayed long-term stability to glucose. These results indicate that the graphene-CuO nanocomposites are promising candidates for the non-enzymatic detection of glucose.