Hexahydrocannabinol Pharmacology, Toxicology, and Analysis: The FirstEvidence for a Recent New Psychoactive Substance

Abstract

Similarly to other NPS, the HHC represents a cheaper alternative to the controlled Δ<sup>9</sup>-THC. Its monitoring is a crucial challenge for toxicological and forensic purposes. To this concern, it is essential to further investigate HHC to support health providers in the identification of related intoxications.

References

Page 1

	Year	Citations
Molecular characterization of a peripheral receptor for cannabinoids Sean Munro, Kerrie L. Thomas, Muna Abu-Shaar Nature Cannabis UseMolecular PharmacologyFunctional SelectivityMedicineReceptor (Biochemistry)	1993	5K
Structure of a cannabinoid receptor and functional expression of the cloned cDNA Lisa A. Matsuda, Stephen J. Lolait, Michael Brownstein, Nature Cannabis UseMolecular PharmacologyBiochemistryFunctional ExpressionMedicine	1990	5K
RETRACTED ARTICLE: Crystal structures of agonist-bound human cannabinoid receptor CB1 Tian Hua, Kiran Vemuri, Spyros P. Nikas, Nature	2017	500
Isolation and structure of .DELTA.+- tetrahydrocannabinol and other neutral cannabinoids from hashish Yechiel Gaoni, Raphael Mechoulam Journal of the American Chemical Society Altmetric Attention ScoreChemical BiologyDrug ClassCannabinoid PharmacologyMolecular Pharmacology	1971	364
Cannabinoids in health and disease Natalya M. Kogan, Raphael Mechoulam Dialogues in Clinical Neuroscience Cannabis UseSubstance AbusePsychoactive DrugPsychiatryAddiction	2007	221
1-Δ <sup>9</sup> -Tetrahydrocannabinol: Neurochemical and Behavioral Effects in the Mouse David Holtzman, Richard Lovell, Jerome H. Jaffe, Science NeuropsychologyNeurotransmitterWhole BrainPsychopharmacologyBrain Amines	1969	206
A novel probe for the cannabinoid receptor William A. Devane, Aviva Breuer, Tzviel Sheskin, Journal of Medicinal Chemistry	1992	203
STRUCTURAL REQUIREMENTS FOR CANNABINOID ACTIVITY* H. Edery, Yona Grunfeld, Zvi Ben‐Zvi, Annals of the New York Academy of Sciences Cannabis UseHealth SciencesBiochemistryFunctional SelectivityAddiction	1971	116
Modulation of rat brain opioid receptors by cannabinoids. P J Vaysse, Eliot L. Gardner, R. Suzanne Zukin Journal of Pharmacology and Experimental Therapeutics	1987	100
Δ9-Tetrahydrocannabinol acts as a partial agonist/antagonist in mice Carol A. Paronis, Spyros P. Nikas, Vidyanand G. Shukla, Behavioural Pharmacology	2012	92

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