Menaquinone-4 prevents medication-related osteonecrosis of the jaw through the SIRT1 signaling-mediated inhibition of cellular metabolic stresses-induced osteoblast apoptosis

Vitamin K ₂ Is a Mitochondrial Electron Carrier That Rescues Pink1 Deficiency

Melissa Vos, Giovanni Esposito, Janaka N. Edirisinghe et al. · Science · 2012 · 352 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

NAD+ improves cognitive function and reduces neuroinflammation by ameliorating mitochondrial damage and decreasing ROS production in chronic cerebral hypoperfusion models through Sirt1/PGC-1α pathway

Yao Zhao, Jiawei Zhang, Yaling Zheng et al. · Journal of Neuroinflammation · 2021 · 340 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Vascular Smooth Muscle Cell Sirtuin 1 Protects Against DNA Damage and Inhibits Atherosclerosis

Isabelle Gorenne, Sheetal Kumar, Kelly Gray et al. · Circulation · 2012 · 270 citations

Life Sciences, Cell Biology, Molecular Biology +17

Melatonin protects mouse testes from palmitic acid‐induced lipotoxicity by attenuating oxidative stress and DNA damage in a SIRT1‐dependent manner

Dejun Xu, Lingbin Liu, Yongju Zhao et al. · Journal of Pineal Research · 2020 · 232 citations

Life Sciences, Biochemistry, Pharmacology +15

Bioactive Nanoenzyme Reverses Oxidative Damage and Endoplasmic Reticulum Stress in Neurons under Ischemic Stroke

Guanning Huang, Jiankun Zang, Lizhen He et al. · ACS Nano · 2021 · 226 citations

Life Sciences, Biochemistry, Neuroscience +17