Inhibition of <scp>VEGFR2</scp> and <scp>EGFR</scp> signaling cooperatively suppresses the proliferation of oral squamous cell carcinoma

Abstract

VEGFR-mediated signaling would be an alternative signaling pathway for the survival of OSCC cells under the disruption of EGFR signaling. These results highlight the clinical application of VEGFR inhibitors in the development of multi-molecular-targeted therapeutics against OSCC.