Should Buprenorphine Be Considered a First-Line Opioid for the Treatment of Moderate to Severe Cancer Pain?

CDC Clinical Practice Guideline for Prescribing Opioids for Pain<b>—</b>United States, 2022

Deborah Dowell, Kathleen Ragan, Christopher M. Jones et al. · MMWR Recommendations and Reports · 2022 · 1.7K citations · Full text

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Opioids and the Management of Chronic Severe Pain in the Elderly: Consensus Statement of an International Expert Panel with Focus on the Six Clinically Most Often Used World Health Organization step III Opioids (Buprenorphine, Fentanyl, Hydromorphone, Methadone, Morphine, Oxycodone)

Joseph V. Pergolizzi, Rainer H. Böger, Keith Budd et al. · Pain Practice · 2008 · 859 citations

Medicine, Pharmacology, Pharmacotherapy +17

Buprenorphine induces ceiling in respiratory depression but not in analgesia

Albert Dahan, Ashraf Yassen, Raymonda Romberg et al. · British Journal of Anaesthesia · 2006 · 369 citations

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Comparison of the respiratory effects of intravenous buprenorphine and fentanyl in humans and rats

Albert Dahan, Ashraf Yassen, Hans Bijl et al. · British Journal of Anaesthesia · 2005 · 329 citations

Medicine, Pharmacokinetics, Pharmacology +10

Are strong opioids equally effective and safe in the treatment of chronic cancer pain? A multicenter randomized phase IV ‘real life’ trial on the variability of response to opioids

Oscar Corli, Irene Floriani, Mauro Montanari et al. · Annals of Oncology · 2016 · 151 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +14