TOPK promotes the growth of esophageal cancer in vitro and in vivo by enhancing YB1/eEF1A1 signal pathway

Identification of genomic alterations in oesophageal squamous cell cancer

Yongmei Song, Lin Li, Yunwei Ou et al. · Nature · 2014 · 1.1K citations

Tumor Biology, Somatic Variant, Esophageal Cancer +6

Genetic landscape of esophageal squamous cell carcinoma

Yibo Gao, Zhao-Li Chen, Jia-Gen Li et al. · Nature Genetics · 2014 · 708 citations

Tumor Biology, Genetic Landscape, Esophagus +7

Large-scale and high-resolution mass spectrometry-based proteomics profiling defines molecular subtypes of esophageal cancer for therapeutic targeting

Wei Liu, Lei Xie, Yaohui He et al. · Nature Communications · 2021 · 154 citations · Full text

Novel TOPK Inhibitor HI-TOPK-032 Effectively Suppresses Colon Cancer Growth

Dong Joon Kim, Yan Li, Kanamata Reddy et al. · Cancer Research · 2012 · 112 citations

Chemoprevention Strategy, Gastrointestinal Oncology, Medicine +14

Targeting PBK/TOPK decreases growth and survival of glioma initiating cells in vitro and attenuates tumor growth in vivo

Mrinal Joel, Awais A. Mughal, Zanina Grieg et al. · Molecular Cancer · 2015 · 100 citations · Full text