Concepedia

FABP5 suppresses colorectal cancer progression via mTOR-mediated autophagy by decreasing FASN expression

Mujie Ye, Chunhua Hu, Tiaotiao Chen, Ping Yu, Jinhao Chen, Feiyu Lu, Lin Xu, Yuan Zhong, Lijun Yan, Jingbao Kan,

International Journal of Biological Sciences · 2023 · 62 citations · 27 references

DOIFull text

Open access

Concepts

Abstract

axis in tumor progression and uncover a potential mechanism linking lipid metabolism to development of CRC, providing novel therapeutic targets for future interventions.

References

27

Reprogramming of lipid metabolism in cancer-associated fibroblasts potentiates migration of colorectal cancer cells

Jin Gong, Yiyun Lin, Huaqin Zhang et al. · Cell Death and Disease · 2020 · 277 citations · Full text

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FABP5 promotes lymph node metastasis in cervical cancer by reprogramming fatty acid metabolism

Chunyu Zhang, Yuandong Liao, Pan Liu et al. · Theranostics · 2020 · 185 citations · Full text

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NCAPD3 enhances Warburg effect through c-myc and E2F1 and promotes the occurrence and progression of colorectal cancer

Zuolei Jing, Qianmei Liu, Xinyuan He et al. · Journal of Experimental & Clinical Cancer Research · 2022 · 171 citations · Full text

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FASN promotes lymph node metastasis in cervical cancer via cholesterol reprogramming and lymphangiogenesis

Qiqiao Du, Pan Liu, Chunyu Zhang et al. · Cell Death and Disease · 2022 · 133 citations · Full text

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Genetic Ablation of the Fatty Acid–Binding Protein FABP5 Suppresses HER2-Induced Mammary Tumorigenesis

Liraz Levi, Glenn P. Lobo, Mary Kathryn Doud et al. · Cancer Research · 2013 · 110 citations · Full text

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