Structures of sperm flagellar doublet microtubules expand the genetic spectrum of male infertility

Basic local alignment search tool

Stephen F. Altschul, Warren Gish, Webb Miller et al. · Journal of Molecular Biology · 1990 · 94.5K citations

Life Sciences, Bioinformatics, Sequence Analysis +3

<i>Coot</i>: model-building tools for molecular graphics

Paul Emsley, Kevin Cowtan · Acta Crystallographica Section D Biological Crystallography · 2004 · 31.4K citations · Full text

Life Sciences, Bioinformatics, Biology +17

Fast, scalable generation of high‐quality protein multiple sequence alignments using Clustal Omega

Fabian Sievers, Andreas Wilm, David Dineen et al. · Molecular Systems Biology · 2011 · 16.2K citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +7

SWISS-MODEL: homology modelling of protein structures and complexes

Andrew Waterhouse, Martino Bertoni, Stefan Bienert et al. · Nucleic Acids Research · 2018 · 13.6K citations · Full text

Life Sciences, Biochemistry, Bioinformatics +15

cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination

Ali Punjani, John L. Rubinstein, David J. Fleet et al. · Nature Methods · 2017 · 10.7K citations

Life Sciences, Bioinformatics, Biophysics +12