Cadmium exposure caused cardiotoxicity in common carps (Cyprinus carpio L.): miR-9-5p, oxidative stress, energetic impairment, mitochondrial division/fusion imbalance, inflammation, and autophagy

Metformin Inhibits the NLRP3 Inflammasome via AMPK/mTOR-dependent Effects in Diabetic Cardiomyopathy

Fan Yang, Ying� Qin, Yueqiu Wang et al. · International Journal of Biological Sciences · 2019 · 457 citations · Full text

Life Sciences, Cardiology, Pharmacology +17

Cisplatin-induced nephrotoxicity is associated with oxidative stress, redox state unbalance, impairment of energetic metabolism and apoptosis in rat kidney mitochondria

Neife Aparecida Guinaim dos Santos, C. S. Catão, Nádia Maria Martins et al. · Archives of Toxicology · 2007 · 326 citations

Life Sciences, Nephrology, Toxicology +17

Polystyrene microplastics-induced cardiotoxicity in chickens via the ROS-driven NF-κB-NLRP3-GSDMD and AMPK-PGC-1α axes

Yue Zhang, Kai Yin, Dongxu Wang et al. · The Science of The Total Environment · 2022 · 290 citations

Agriculture, Poultry Science, Toxicology +16

Attenuation of Lipopolysaccharide-Induced Acute Lung Injury by Hispolon in Mice, Through Regulating the TLR4/PI3K/Akt/mTOR and Keap1/Nrf2/HO-1 Pathways, and Suppressing Oxidative Stress-Mediated ER Stress-Induced Apoptosis and Autophagy

Ching‐Ying Huang, Jeng‐Shyan Deng, Wen‐Chin Huang et al. · Nutrients · 2020 · 278 citations · Full text

Life Sciences, Immunology, Pharmacology +17

Induction of autophagy via the ROS-dependent AMPK-mTOR pathway protects copper-induced spermatogenesis disorder

Hongrui Guo, Yujuan Ouyang, Heng Yin et al. · Redox Biology · 2021 · 263 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17