Concepedia

AMG 145, a Monoclonal Antibody Against PCSK9, Facilitates Achievement of National Cholesterol Education Program–Adult Treatment Panel III Low-Density Lipoprotein Cholesterol Goals Among High-Risk Patients

Nihar R. Desai, Robert P. Giugliano, Jing Zhou, Payal Kohli, Ransi Somaratne, Elaine Hoffman, Thomas Liu, Robert C. Scott, Scott M. Wasserman, Marc S. Sabatine

Journal of the American College of Cardiology · 2013 · 52 citations · 5 references

DOI

Concepts

References

5

Safety and Efficacy of a Monoclonal Antibody to Proprotein Convertase Subtilisin/Kexin Type 9 Serine Protease, SAR236553/REGN727, in Patients With Primary Hypercholesterolemia Receiving Ongoing Stable Atorvastatin Therapy

James M. McKenney, Michael J. Koren, Dean J. Kereiakes et al. · Journal of the American College of Cardiology · 2012 · 507 citations

, , +13

Efficacy, safety, and tolerability of a monoclonal antibody to proprotein convertase subtilisin/kexin type 9 in combination with a statin in patients with hypercholesterolaemia (LAPLACE-TIMI 57): a randomised, placebo-controlled, dose-ranging, phase 2 study

Robert P. Giugliano, Nihar R. Desai, Payal Kohli et al. · The Lancet · 2012 · 424 citations

, , +10

Can Low-Density Lipoprotein Be Too Low? The Safety and Efficacy of Achieving Very Low Low-Density Lipoprotein With Intensive Statin Therapy

Stephen D. Wiviott, Christopher P. Cannon, David A. Morrow et al. · Journal of the American College of Cardiology · 2005 · 342 citations

, , +13

Trends in High Levels of Low-Density Lipoprotein Cholesterol in the United States, 1999-2006

Elena V. Kuklina · JAMA · 2009 · 136 citations

, , +16

Achieving Optimal Lipid Goals in Patients With Coronary Artery Disease

Dean G. Karalis, Raghunandan Dudda Subramanya, Scott E. Hessen et al. · The American Journal of Cardiology · 2011 · 43 citations · Full text

, , +13