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Publication | Open Access

The phospholipid transporter PITPNC1 links KRAS to MYC to prevent autophagy in lung and pancreatic cancer

DOIFull Paper Access

21

Citations

69

References

2023

Year

Rodrigo Entrialgo‐Cadierno, Cristina Cueto‐Ureña, Connor Welch, Iker Feliu, Irati Macaya, Laura Vera, Xabier Morales, Sandra Vietti Michelina, Pietro Scaparone, Inés López,
Molecular Cancer

Abstract

Our data highlight the functional and clinical relevance of PITPNC1 in LUAD and PDAC. Moreover, PITPNC1 constitutes a new mechanism linking KRAS to MYC, and controls a druggable transcriptional network for combinatorial treatments.

References

YearCitations

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