Concepedia

Safety and efficacy of valbenazine for the treatment of chorea associated with Huntington's disease (KINECT-HD): a phase 3, randomised, double-blind, placebo-controlled trial

Erin Furr Stimming, Daniel O. Claassen, Elise Kayson, Jody Goldstein, Raja Mehanna, Hui Zhang, Grace Liang, Dietrich Haubenberger, Jamie Adams, Christopher A. Beck,

The Lancet Neurology · 2023 · 63 citations · 14 references

Concepts

MedicinePharmacologyPharmacotherapyNeurodegenerationNeuropharmacologyPsychopharmacologyHuntington DiseaseNeurodegenerative Disease PharmacologyNeurodegenerative Disease PharmacotherapyNeurodegenerative DiseasesNeurodegenerative DisordersHuntington Disease PharmacotherapyHuntington's Disease PharmacotherapyPlacebo-controlled Efficacy Assessment

References

14

Tetrabenazine as antichorea therapy in Huntington disease

Neurology · 2006 · 459 citations

Medicine, Pharmacology, Pharmacotherapy +17

Effect of Deutetrabenazine on Chorea Among Patients With Huntington Disease

Samuel Frank, Claudia Testa, David Stamler et al. · JAMA · 2016 · 398 citations · Full text

Medicine, Neurology, Pharmacology +16

Pharmacologic Characterization of Valbenazine (NBI-98854) and Its Metabolites

Dimitri E. Grigoriadis, Evan Smith, Sam R.J. Hoare et al. · Journal of Pharmacology and Experimental Therapeutics · 2017 · 253 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

Evidence of a neurologically based "denial of illness" in patients with Huntington's disease

A. Wallace Deckel, Diane M. Morrison · Archives of Clinical Neuropsychology · 1996 · 64 citations · Full text

Medicine, Neurology, Neuroscience +17

The Impact of Anosognosia on Clinical and Patient-Reported Assessments of Psychiatric Symptoms in Huntington’s Disease

David A. Isaacs, Jessie S. Gibson, Jeffrey Stovall et al. · Journal of Huntington s Disease · 2020 · 41 citations

Medicine, Neurology, Psychiatry +17