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Suramin ameliorates osteoarthritis by acting on the Nrf2/HO-1 and NF-κB signaling pathways in chondrocytes and promoting M2 polarization in macrophages

InflammationRheumatologyAnti-inflammatorySignal TransductionM2 PolarizationMusculoskeletal ResearchMedicineCartilage DegenerationChronic InflammationOsteoarthritisPharmacologyCell BiologyCell SignalingInflammatory ArthritisOxidative StressMolecular Signaling