Concepedia

Technical considerations for the implementation of the multi-attribute-method by mass spectrometry in a quality control laboratory

Thomas Pohl, Annick Gervais, Eef H.C. Dirksen, Valerio D’Alessio, Karoline Bechtold-Peters, Will Burkitt, Li Cao, Simone Greven, Andrew Lennard, Xue Li,

European Journal of Pharmaceutics and Biopharmaceutics · 2023 · 15 citations · 52 references

DOI

Concepts

References

52

Identification and Characterization of Deamidation Sites in the Conserved Regions of Human Immunoglobulin Gamma Antibodies

Dirk Chelius, Douglas S. Rehder, Pavel V. Bondarenko · Analytical Chemistry · 2005 · 263 citations

, , +17

Quantitative Assessment of In-solution Digestion Efficiency Identifies Optimal Protocols for Unbiased Protein Analysis

Ileana R. León, Veit Schwämmle, Ole N. Jensen et al. · Molecular & Cellular Proteomics · 2013 · 261 citations · Full text

, , +17

Development of a quantitative mass spectrometry multi-attribute method for characterization, quality control testing and disposition of biologics

Richard S. Rogers, Nancy S. Nightlinger, Brittney Livingston et al. · mAbs · 2015 · 222 citations · Full text

, , +16

A study in glycation of a therapeutic recombinant humanized monoclonal antibody: Where it is, how it got there, and how it affects charge-based behavior

Cynthia Quan, Emily W. Alcala, Irena Petkovska et al. · Analytical Biochemistry · 2007 · 201 citations

, , +16

An improved trypsin digestion method minimizes digestion-induced modifications on proteins

Da Ren, Gary D. Pipes, Dingjiang Liu et al. · Analytical Biochemistry · 2009 · 191 citations

, , +11