Concepedia

Anti-cancer effect of fenbendazole-incorporated PLGA nanoparticles in ovarian cancer

Chi‐Son Chang, Ji‐Yoon Ryu, June-Kuk Choi, Young-Jae Cho, Jung‐Joo Choi, Jae Ryoung Hwang, Ju‐Yeon Choi, Joseph J. Noh, Chan Mi Lee, Ji Eun Won,

Journal of Gynecologic Oncology · 2023 · 15 citations · 28 references

DOI Full text

Open access

Abstract

FZ-incorporated PLGA nanoparticles exerted significant anti-cancer effects in EOC cells and xenograft models including PDX. These results warrant further investigation in clinical trials.

References

28

Cancer statistics, 2022

Rebecca L. Siegel, Kimberly D. Miller, Hannah E. Fuchs et al. · CA A Cancer Journal for Clinicians · 2022 · 17.9K citations · Full text

Epidemiology Of Cancer, Population Health Sciences, Cancer Registration +18

Dexamethasone/PLGA microspheres for continuous delivery of an anti-inflammatory drug for implantable medical devices

Tammy Hickey, D. L. Kreutzer, Diane J. Burgess et al. · Biomaterials · 2002 · 266 citations

Nanomedicine, Dexamethasone/plga Microspheres, Engineering +11

Mebendazole elicits a potent antitumor effect on human cancer cell lines both in vitro and in vivo.

Tapas Mukhopadhyay, Ji-ichiro Sasaki, Rajagopal Ramesh et al. · PubMed · 2002 · 181 citations

Normal Wi38, Medicine, Potent Antitumor Effect +14

The anthelmintic drug mebendazole induces mitotic arrest and apoptosis by depolymerizing tubulin in non-small cell lung cancer cells.

J. Sasaki, Rajagopal Ramesh, Sunil Chada et al. · PubMed · 2002 · 171 citations

Oncology, Strong Microtubule Inhibitors, Antiparasitic Agent +14

CD44-Targeting PLGA Nanoparticles Incorporating Paclitaxel and FAK siRNA Overcome Chemoresistance in Epithelial Ovarian Cancer

Yeongseon Byeon, Jeong‐Won Lee, Whan Soo Choi et al. · Cancer Research · 2018 · 122 citations