Neuron-Derived Exosomes Promote the Recovery of Spinal Cord Injury by Modulating Nerve Cells in the Cellular Microenvironment of the Lesion Area

Neurotoxic reactive astrocytes are induced by activated microglia

Shane A. Liddelow, Kevin A. Guttenplan, Laura Clarke et al. · Nature · 2017 · 8K citations · Full text

Medicine, Neurobiology, Neuroscience +14

Astrocyte scar formation aids central nervous system axon regeneration

Mark A. Anderson, Joshua E. Burda, Yilong Ren et al. · Nature · 2016 · 1.9K citations · Full text

Medicine, Neurobiology, Neuroscience +10

Glial Scar Borders Are Formed by Newly Proliferated, Elongated Astrocytes That Interact to Corral Inflammatory and Fibrotic Cells via STAT3-Dependent Mechanisms after Spinal Cord Injury

I. Wanner, Mark A. Anderson, Bao‐Liang Song et al. · Journal of Neuroscience · 2013 · 834 citations · Full text

Medicine, Neurobiology, Neuroscience +17

Cellular and Molecular Mechanisms of Glial Scarring and Progressive Cavitation:<i>In Vivo</i>and<i>In Vitro</i>Analysis of Inflammation-Induced Secondary Injury after CNS Trauma

Michael T. Fitch, Catherine Doller, Colin K. Combs et al. · Journal of Neuroscience · 1999 · 478 citations · Full text

Medicine, Neurobiology, Neuroscience +17

Neuron-derived exosomes-transmitted miR-124-3p protect traumatically injured spinal cord by suppressing the activation of neurotoxic microglia and astrocytes

Dongdong Jiang, Fangyi Gong, Xuhui Ge et al. · Journal of Nanobiotechnology · 2020 · 310 citations · Full text

Medicine, Neurobiology, Neuroscience +17