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Publication | Open Access

IGF2BP2 promotes colorectal cancer progression by upregulating the expression of TFRC and enhancing iron metabolism

DOIFull Paper Access

34

Citations

22

References

2023

Year

Tianyue Liu, Chenchen Hu, Chenying Han, Siyi Mao, Wenxin Zhang, Yiming Xu, Yuanjie Sun, Dongbo Jiang, Xi-Yang Zhang, Jiaxing Zhang,
Biology Direct

Abstract

IGF2BP2 regulates TFRC mRNA methylation via METTL4, thereby regulating iron metabolism and promoting CRC growth. Our study highlights the key roles of IGF2BP2 in CRC carcinogenesis and the iron transport pathways.

References

YearCitations

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