A Case of Multidrug-Resistant Klebsiella pneumoniae Treated with Carrimycin

Abstract

One of the most pressing emerging issues in bacterial resistance is multidrug-resistant <i>Klebsiella pneumoniae</i>. The treatment of <i>K. pneumoniae</i> infections is often problematic because of the lack of available therapeutic options, leading to negative effects on morbidity, mortality, and healthcare-associated costs. Carrimycin is a macrolide antibiotic with good antibacterial effects. In this study, we report a patient diagnosed with multidrug-resistant <i>K. pneumoniae</i> infection who was treated with carrimycin. The patient presented with cough, expectoration, dyspnea, and severe hypoxemia requiring noninvasive ventilation. We successively used a variety of antibiotics, including meropenem, tigecycline, and polymyxin, with unsatisfactory results. Finally, we used carrimycin, and the patient's condition improved, resulting in hospital discharge. Therefore, for patients with multidrug-resistant <i>K. pneumoniae</i> infection that does not respond to conventional anti-infective treatments, carrimycin can be considered a treatment option.